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Rangel, who has served northern Manhattan since 1971, has been accused of using rent-stabilized apartments for a campaign office, failing to report more than $600,000 of income and not reporting and paying taxes on a villa in the Dominican Republic.

While some Harlem residents told NY1 that the 80-year-old Democrat helped the neighborhood in his four decades of public service, others said new blood needs to fill the Congress seat.

"It's somewhat of a slight smear on a great career. He's had a great career in this area," said one local.

"He has done a lot for Harlem. It's kind of hard not to defend him.... But it's politics. I guess it's his turn for his dirty laundry," said another.

"I'm glad, because he's been in office for like, 40 years? I think it's time for a change," said a third.

"I think that 13 [charges] is an unlucky number. Charlie Rangel should think about retiring, he's 80 years old. He's had a great career," said a fourth.

Rangel faces a crowded primary in September, when he is scheduled to go on trial in the House.

Rangel has denied any wrongdoing.